ʻO ke gula kekahi o nā mea paʻa kemika, a loaʻa i nā ʻāpana gula nanoscale nā ​​waiwai kino a me nā waiwai kemika.I ka makahiki 1857, ua hoemi o Faraday i ka wai AuCl4-wai me ka phosphorus no ka loaa ana o ka colloidal solution o na nanoppowders gula, ka mea i uhai i ka ike o kanaka i ke kala o ke gula.Ua ʻike pū ʻia nā ʻāpana gula Nano i ka fluorescence, supramolecular a me ka molecular recognition properties.Ma muli o nā waiwai kūikawā o nā pauka gula nano i loaʻa iā lākou nā manaʻo noiʻi ākea loa i nā kahua o nā biosensors, photochemical a me electrochemical catalysis, a me nā mea optoelectronic.I nā makahiki i hala iho nei, ma muli o ke ʻano o ka hoʻololi ʻulaʻula o ka ʻili plasmon resonance peak o Au nanoparticles ma hope o ka adsorption, ua aʻo ʻia ka DNA a me nā molekala kalapona i hoʻouka ʻia me nā mea nano Au a loaʻa ka pono i nā kula o ka pale ʻana, calibration. a me ka tracer.

Nā nanoparticles gulama ke ʻano he ʻano nanoparticles, makemake nui ʻia ma muli o ko lākou kūpaʻa, homogeneity a me ka biocompatibility.ʻO ka ʻili o ka plasmon resonance waiwai a me ka hōʻuluʻulu ʻana o nā ʻāpana nano gula, a me ko lākou hilinaʻi ʻana i ke kaiapuni o waho, e hoʻohana nui ʻia i ka ʻike colorimetric.ʻO nā ikaika i hōʻike ʻia no ka hōʻuluʻulu ʻana o nā ʻāpana nano me ka hoʻopaʻa ʻana i ka hydrogen, ka pilina pūnaewele ionic ligand, ka hoʻohui metala, a me ka hoʻokomo ʻana o ka poʻe hoʻokipa.Me ka hoʻohana ʻana i ka sodium citrate ma ke ʻano he stabilizer, ua hoʻohui maikaʻi ʻia nā nanoparticles gula i hoʻololi ʻia ka sodium citrate a hoʻohana ʻia ma ke ʻano he colorimetric probes.Hoʻopiʻi maikaʻi ʻia ka ʻili o ka nano gula probe a hiki ke maʻalahi ke hoʻohui ʻia me nā molekele i hoʻopiʻi maikaʻi ʻia ma o ka pilina electrostatic.Ma ka BR buffer solution ma ka pH 4.6, ua hoʻopiʻi maikaʻi ʻia ka propranolol ma muli o ka protonation, no laila hiki ke hoʻohui ʻia me nā nanoparticles gula, ka hopena i ka hoʻololi ʻana i ke kala o ka ʻōnaehana, i mea e hoʻokumu ai i kahi ala ʻike colorimetric maʻalahi no propranolol.I ka manawa like, me ka hui pū ʻana o nā pauka nano gula, e hoʻonui pū ka RRS ikaika o ka ʻōnaehana, no laila ke ʻano RRS me kahi spectrophotometer fluorescence maʻalahi e like me ka mea ʻike i hoʻokumu ʻia e ʻike pono i ka propranolol.Ma muli o ka sodium citrate-modified gold nan oparticles, colorimetric a me RRS nā ʻano no ka hoʻoholo ʻana i ka propranolol.

Loaʻa iā Hongwu Nano ka lako no ka manawa lōʻihi a paʻa i nā ʻāpana nano gula kiʻekiʻe (Au), hōʻoia maikaʻi, kūʻai pololei ʻana i nā hale hana, a me nā kumukūʻai hoʻokūkū.E ʻoluʻolu, mai kānalua e kelepona mai iā mākou no ka ʻike hou aku.