Ngati tsitsi limakhala vuto kwa akuluakulu, kenako mano akuwola (dzina la sayansi) ndi vuto lamutu) ndi vuto lamutu wamba kwa anthu azaka zonse.

Malinga ndi ziwerengero, matenda a ma denties a carries a madoko akudziko langa ali ndi zaka zopitilira 50 Ngati sakuthandizidwa pakapita nthawi, matenda ofala a mano a mano am'madontho amadwala ndi apication, ndipo ngakhale kuyambitsa mafupa a alveor, komwe kungasokoneze thanzi ndi moyo wa wodwalayo. Tsopano, matendawa mwina adakumana ndi "Nemesis."

Ku American Fianc Society (ACS) Msonkhano ndi chiwonetsero cha Fall 2020, ofufuza ku Yunivesite ya Illium Natinois omwe angalepheretse madongosolo am'mano. Pakadali pano, ofufuza agwiritsa ntchito patent, ndipo kukonzekera kungagwiritsidwe ntchito ku zipatala za mano mtsogolo.

Pali mitundu yoposa 700 ya mabakiteriya m'mwambo ya munthu. Pakati pawo, palibe mabakiteriya okha omwe amathandizira kugaya chakudya kapena kuwongolera tizilombo tina, komanso mabakiteriya oyipa kuphatikizapo Muspfetococcus mutans. Mabakiteriya ovulaza amenewa amatha kutsatira mano ndikusonkhanitsa kuti apange "a biofilm", amatulutsa zochokera ku Acirickect yomwe imapanga njira yonyana nayo inayameni, kuwomba kwa mano ".

Zachipatala, kusakhazikika kwa scheside, siliva wasiliva kapena siliva wa diarine nthawi zambiri kumagwiritsidwa ntchito poletsa chigoli cha mano komanso kupewa kuwola kwa mano. Palinso maphunziro omwe akuyesera kugwiritsa ntchito nanoparticles opangidwa ndi zinc oxide, mkuwa oxide, etc. Kuthandizira kuwonongeka kwa mano. Koma vuto ndilakuti pali mano opitilira 4 mkamwa mwanu, ndipo onse ali pachiwopsezo chodzazidwa ndi mabakiteriya. Kugwiritsidwa mobwerezabwereza kwa mankhwalawa kumatha kupha maselo opindulitsa ndipo ngakhale kuyambitsa matenda osokoneza bongo osokoneza bongo.

Chifukwa chake, ofufuza akuyembekeza kupeza njira yotetezera mabakiteriya opindulitsa amkamwa ndikupewa kuwola kwa dzino. Adatembenuza chidwi chawo ku Cerium oxide nanoparticles (molecular formula: Ceo2). Tinthu tating'onoting'ono ndi chimodzi mwazinthu zofunika kwambiri za antibacterial ndipo zili ndi zoopsa zochepa kwambiri maselo wamba komanso njira ya antibacterial kutengera kutembenuka kosinthika. Mu 2019, ofufuza ku yunivesite ya Nankii adatukwana mwadongosolo la antibacterial waCeamu Oxide Nanoparticlesmu zida za sayansi.

Malinga ndi lipoti la ofufuzawo pamsonkhanowu, iwo amapanga Cerium oxide nanoparticles mwa kusungunula cerium kapena amagwiritsa ntchito mphamvu yamadzi pa "biofilm" zopangidwa ndi ma mutans a streptococcus. Zotsatira zake zinawonetsa kuti ngakhale mabati a cerium oxide sakanachotsa "biofilm" yomwe idapezekapo, adachepetsa 40%. Munthawi yofananawo, odana ndi anti-calturective active a Citrate salephera kuzengereza "biofilm". Kukula kwa "nembanemba".

Wofufuza wamkulu wa ntchitoyi, Russell Pesavento of Illinois ku Chicago, anati: "Ubwino wa njirayi ndichakuti zikuwoneka kuti zikuwoneka zopanda mphamvu pakamwa mabakiteriya. Ma nanoparticles amangopewa tizilombo totsatira kutsata chinthucho ndikupanga bifilm. Ndipo zoopsa za tinthu tazomera komanso zokhudzana ndi metaboliczo m'malale apakamwa m'mbale a petri ndizochepa kuposa siliva yamankhwala. " 

Pakadali pano, timu ikuyesera kugwiritsa ntchito zokutira kukhazikika pa nanoparticles pa ph kapena zofooka alkaline ph pafupi ndi malovu. M'tsogolomu, ofufuza adzayesa mphamvu ya mankhwalawa pamaselo a anthu mu thirakiti lotsika kwambiri mu maluwa okwanira amkamwa apakamwa, kuti apereke odwala omwe ali ndi chitetezo chabwino.