Golide wa Colloidal

Colloidal Gold nanoparticlesakhala akugwiritsidwa ntchito ndi ojambula kwa zaka mazana ambiri chifukwa amalumikizana ndi kuwala kowoneka kuti apange mitundu yowala.Posachedwapa, chinthu chapadera cha photoelectric ichi chafufuzidwa ndikugwiritsidwa ntchito m'zinthu zamakono monga maselo a dzuwa, ma sensor probes, othandizira achire, machitidwe operekera mankhwala opangira mankhwala mu biological and medical application, conductors zamagetsi, ndi catalysis.The kuwala ndi zamagetsi katundu wa nanoparticles golide akhoza kusintha ndi kusintha kukula, mawonekedwe, umagwirira pamwamba ndi aggregation boma.

Njira yothetsera golide wa colloidal imatanthawuza chitsulo chagolide chokhala ndi gawo lobalalika pakati pa 1 ndi 150 nm.Ndi ya heterogeneous heterogeneous system, ndipo mtundu wake ndi lalanje mpaka wofiirira.Kugwiritsa ntchito golide wa colloidal monga chizindikiro cha immunohistochemistry kunayamba mu 1971. Faulk et al.Anagwiritsa ntchito ma electron microscopy immunocolloidal gold staining (IGS) kuwona Salmonella.

Yolembedwa pa antibody yachiwiri (igG ya kavalo yotsutsana ndi munthu), njira yodetsa golide yosadziwika bwino idakhazikitsidwa.Mu 1978, geoghega adapeza kugwiritsa ntchito zolembera zagolide pagalasi lowala.Kugwiritsa ntchito golide wa colloidal mu immunochemistry kumatchedwanso immunogold.Pambuyo pake, akatswiri ambiri adatsimikiziranso kuti golidi wa colloidal amatha kutulutsa mapuloteni mokhazikika komanso mofulumira, ndipo ntchito yachilengedwe ya mapuloteniwo sinasinthe kwambiri.Ikhoza kugwiritsidwa ntchito ngati kafukufuku kwa malo enieni a selo pamwamba ndi okhudza maselo ambiri polysaccharides, mapuloteni, polypeptides, ma antigen, mahomoni, nucleic zidulo ndi zina zamoyo macromolecules.Ikhoza kugwiritsidwanso ntchito tsiku ndi tsiku immunodiagnosis ndi immunohistochemical localization, motero mu matenda a matenda Ndipo kugwiritsa ntchito kuzindikira mankhwala ndi mbali zina zakhala zofunika kwambiri.Pakadali pano, madontho a immunogold pamlingo wa electron maikulosikopu (IGS), madontho a immunogold pamlingo wa microscope (IGSS), ndi mawanga a immunogold pamlingo wa macroscopic akuchulukirachulukira kukhala zida zamphamvu pakufufuza kwasayansi komanso kuzindikira kwachipatala.