Niba guta umusatsi ari ikibazo kubantu bakuru, noneho kubora amenyo (izina ryubumenyi caries) nikibazo gikunze kubabaza umutwe kubantu bingeri zose.

Nk’uko imibare ibigaragaza, indwara z’amenyo y’ingimbi mu gihugu cyanjye zirenga 50%, ababana n’indwara z’amenyo mu bantu bageze mu za bukuru barenga 80%, naho mu bageze mu za bukuru, umubare urenga 95%.Niba itavuwe mugihe, iyi ndwara ya bagiteri yamenyo isanzwe itera indwara ya pulpitis na apical periodontitis, ndetse ikanatera uburibwe bwamagufwa ya alveolar namagufwa yumusaya, bizagira ingaruka zikomeye kubuzima nubuzima bwumurwayi.Noneho, iyi ndwara ishobora kuba yarahuye n '“umwanzi.”

Mu nama y’imurikagurisha n’imurikagurisha ry’Abanyamerika (ACS) mu mwaka wa 2020, abashakashatsi bo muri kaminuza ya Illinois i Chicago batangaje ubwoko bushya bw’imisemburo ya cerium nanoparticle ishobora kubuza ko hashyirwaho icyapa cy’amenyo no kwangirika kw'amenyo mu munsi umwe.Kugeza ubu, abashakashatsi basabye ipatanti, kandi imyiteguro irashobora gukoreshwa cyane mu mavuriro y’amenyo mu gihe kiri imbere.

Hariho ubwoko burenga 700 bwa bagiteri mu kanwa k'umuntu.Muri byo, nta bagiteri zifite akamaro gusa zifasha gusya ibiryo cyangwa kugenzura izindi mikorobe, ariko kandi na bagiteri zangiza zirimo na Streptococcus mutans.Indwara ya bagiteri yangiza irashobora kwizirika ku menyo hanyuma igaterana kugirango ikore “biofilm”, ikarya isukari kandi ikabyara aside irike yangiza amenyo, bityo bigatanga inzira yo “kubora amenyo”.

Mubuvuzi, fluoride itangaje, nitrate ya silver cyangwa fluor diamine fluoride ikoreshwa muguhagarika icyapa cy amenyo no kwirinda ko amenyo yangirika.Hariho kandi ubushakashatsi bugerageza gukoresha nanoparticles ikozwe muri zinc oxyde, okiside y'umuringa, nibindi kugirango bavure amenyo.Ariko ikibazo nuko hariho amenyo arenga 20 mumyanya yumunwa yumuntu, kandi yose afite ibyago byo kurandurwa na bagiteri.Gukoresha imiti inshuro nyinshi birashobora kwica selile zingirakamaro ndetse bigatera ikibazo cyo kurwanya ibiyobyabwenge bya bagiteri zangiza.

Kubwibyo, abashakashatsi bizeye gushakisha uburyo bwo kurinda bagiteri zifite akamaro mu cyuho cyo mu kanwa no kwirinda ko amenyo yangirika.Berekeje ibitekerezo byabo kuri cerium oxyde nanoparticles (formula ya molekulari: CeO2).Agace ni kimwe mubikoresho byingenzi bya antibacterial kandi bifite ibyiza byuburozi buke kuri selile zisanzwe hamwe nuburyo bwa antibacterial bushingiye kumyuka ihindagurika.Muri 2019, abashakashatsi bo muri kaminuza ya Nankai bakoze ubushakashatsi kuri gahunda ishoboka ya antibacterial yacerium oxyde nanoparticlesmuri siyansi Ubushinwa Ibikoresho.

Raporo y’abashakashatsi muri iyo nama ivuga ko bakoze cerium oxyde nanoparticles mu gushonga nitrati ya cerium cyangwa sulfate ya amonium mu mazi, kandi biga ku ngaruka z’uduce duto kuri “biofilm” yakozwe na mutans ya Streptococcus.Ibisubizo byagaragaje ko nubwo cerium oxyde nanoparticles idashobora gukuraho “biofilm” ihari, bagabanije gukura kwayo 40%.Mubihe bimeze nkibi, ivuriro rizwi cyane rya anti-cavity agent nitrate ntishobora gutinza "biofilm".Iterambere rya “membrane”.

Umushakashatsi nyamukuru w’uyu mushinga, Russell Pesavento wo muri kaminuza ya Illinois i Chicago, yagize ati: “Ibyiza by’ubu buryo bwo kuvura ni uko bigaragara ko bitangiza mikorobe zo mu kanwa.Nanoparticles izarinda gusa mikorobe kwizirika kubintu no gukora biofilm.Kandi uburozi bw'ingirangingo n'ingaruka za metabolike ku ngirabuzimafatizo zo mu kanwa ka petri ntabwo biri munsi ya nitrate ya feza mu buvuzi busanzwe. ” 

Kugeza ubu, itsinda riragerageza gukoresha ibifuniko kugirango uhagarike nanoparticles kuri pH idafite aho ibogamiye cyangwa alkaline nkeya hafi y amacandwe.Mu bihe biri imbere, abashakashatsi bazagerageza kumenya ingaruka z’ubwo buvuzi ku ngirabuzimafatizo z'umuntu ziri mu nzira yo mu gifu yo mu gifu cyuzuye cya mikorobe yuzuye yo mu kanwa, kugira ngo abarwayi bahabwe umutekano muri rusange.