Kana kurasikirwa kwebvudzi iri dambudziko revakuru, saka kuora kwezino (zita resainzi caries) idambudziko rinowanzoitika remusoro kune vanhu veese mazera.

Zvinoenderana nenhamba, chiitiko chemeno caries pakati pevechiri kuyaruka munyika yangu inopfuura 50%, chiitiko chemazino emazino pakati pevanhu vepakati-kati chinopfuura 80%, uye pakati pevakwegura, chikamu chinopfuura 95%.Kana isina kurapwa nenguva, ichi chinowanzoitika mazino yakaoma tishu utachiona chirwere kuchaita pulpitis uye apical periodontitis, uye kunyange kukonzera kuzvimba alveolar pfupa uye rushaya pfupa, izvo zvichaita zvakakomba kukanganisa utano uye upenyu murwere.Zvino, chirwere ichi chinogona kunge chakasangana ne "nemesis."

PaAmerican Chemical Society (ACS) Virtual Musangano uye Exhibition muFall 2020, vaongorori kubva kuYunivhesiti yeIllinois kuChicago vakashuma rudzi rutsva rwecerium nanoparticle formulation inogona kudzivirira kuumbwa kwemazino plaque uye kuora kwezino mukati mezuva rimwe.Parizvino, vaongorori vakanyorera patent, uye gadziriro yacho inogona kushandiswa zvakanyanya mumakiriniki emazino mune ramangwana.

Kune anopfuura mazana manomwe marudzi emabhakitiriya mumuromo wemunhu.Pakati pavo, hapana mabhakitiriya anobatsira chete anobatsira kugaya zvokudya kana kudzora mamwe ma microorganisms, asiwo mabhakitiriya anokuvadza anosanganisira Streptococcus mutans.Mabhakitiriya anokuvadza akadaro anogona kunamatira kumazino uye kuungana kuti aite "biofilm", anodya shuga uye abudise acidic byproducts iyo inoodza mazino enamel, zvichigadzira nzira ye "kuora kwezino".

Mukiriniki, stannous fluoride, sirivheri nitrate kana sirivheri diamine fluoride inowanzo shandiswa kuvharidzira mazino plaque uye kudzivirira kumwe kuora kwezino.Panewo zvidzidzo zviri kuedza kushandisa nanoparticles yakagadzirwa ne zinc oxide, copper oxide, nezvimwewo kurapa mazino.Asi dambudziko nderekuti mune mazino anopfuura makumi maviri mumuromo wemunhu, uye ese ari panjodzi yekukukurwa nehutachiona.Kudzokororwa kushandiswa kwemishonga iyi kunogona kuuraya masero anobatsira uye kunyange kukonzera dambudziko rekudzivirira kwemishonga yebhakitiriya inokuvadza.

Naizvozvo, vatsvakurudzi vanotarisira kuwana nzira yekudzivirira utachiona hunobatsira mumukanwa uye kudzivirira kuora kwezino.Vakashandura pfungwa dzavo kune cerium oxide nanoparticles (molecular formula: CeO2).Iyo chidimbu ndeimwe yeakakosha antibacterial zvinhu uye ine zvakanakira yakaderera toxicity kune akajairwa maseru uye inorwisa mabhakitiriya mechanicha yakavakirwa pakushandurwa kwevalence kutendeuka.Muna 2019, vaongorori kubva kuNankai University vakaongorora zvine hungwaru nzira inogoneka yeantibacterialcerium oxide nanoparticlesmuScience China Materials.

Maererano nemushumo wevanotsvakurudza pamusangano, vakagadzira cerium oxide nanoparticles nekunyungudutsa cerium nitrate kana ammonium sulfate mumvura, uye vakadzidza migumisiro yezvikamu pa "biofilm" yakagadzirwa neStreptococcus mutans.Zvigumisiro zvakaratidza kuti kunyange zvazvo cerium oxide nanoparticles isingagoni kubvisa "biofilm" iripo, yakaderedza kukura kwayo ne40%.Mumamiriro ezvinhu akafanana, iyo inonzi anti-cavity agent silver nitrate haigone kunonoka "biofilm".Kuvandudzwa kwe "membrane".

Muongorori mukuru wechirongwa ichi, Russell Pesavento weUniversity of Illinois kuChicago, akati: “Chakanakira nzira yekurapa iyi ndechekuti inoita seisina kukuvadza utachiona hwemukanwa.Nanoparticles inongodzivirira ma microorganisms kubva pakunamatira kune chinhu uye kugadzira biofilm.Uye chepfu yehupfu uye metabolic mhedzisiro pamasero emunhu emuromo mune petri dish ishoma pane sirivheri nitrate mukurapwa kwakajairwa. 

Parizvino, timu iri kuyedza kushandisa machira kudzikamisa nanoparticles payakarerekera kana isina kusimba alkaline pH padyo neiyo mate.Mune ramangwana, vaongorori vachayedza mashandiro ekurapa uku pamasero emunhu ari muchikamu chepasi chekudya mune imwe yakazara yemuromo microbial flora, kuitira kupa varwere pfungwa iri nani yekuchengeteka.