Haeba ho lahleheloa ke moriri ke bothata ho batho ba baholo, joale ho bola ha meno (lebitso la saense caries) ke bothata bo tloaelehileng ba hlooho ho batho ba lilemo tsohle.

Ho ea ka lipalo-palo, palo ea batho ba bacha naheng ea heso e feta 50%, palo ea batho ba lilemong tse bohareng e feta 80%, 'me har'a batho ba hōlileng, karolo e ka holimo ho 95%.Haeba e sa phekoloe ka nako, lefu lena le tloaelehileng la baktheria ea meno e thata le tla baka pulpitis le apical periodontitis, esita le ho baka ho ruruha ha lesapo la alveolar le lesapo la mohlahare, le tla ama bophelo bo botle le bophelo ba mokuli ka ho teba.Hona joale, lefu lena le ka 'na la kopana le "sera".

Sebokeng sa Virtual sa American Chemical Society (ACS) le Pontšo ka Fall 2020, bafuputsi ba Univesithing ea Illinois e Chicago ba tlalehile mofuta o mocha oa tlhahiso ea cerium nanoparticle e ka thibelang ho thehoa ha letlapa la meno le ho bola ha leino ka letsatsi le le leng.Hajoale, bafuputsi ba kentse kopo ea patent, mme tokiso e kanna ea sebelisoa haholo litleliniking tsa meno nakong e tlang.

Ho na le mefuta e fetang 700 ea libaktheria molomong oa motho.Har'a tsona, ha ho na libaktheria tse molemo feela tse thusang ho cheka lijo kapa ho laola likokoana-hloko tse ling, empa hape le libaktheria tse kotsi tse akarelletsang Streptococcus mutans.Libaktheria tse joalo tse kotsi li ka khomarela meno 'me tsa bokana ho etsa "biofilm", li ja tsoekere le ho hlahisa lihlahisoa tse nang le acidic tse senyang enamel ea leino, kahoo li bula tsela bakeng sa "ho bola ha leino".

Hangata, stannous fluoride, silver nitrate kapa silver diamine fluoride e sebelisoa hangata ho thibela letlapa la meno le ho thibela ho bola ha leino.Hape ho na le lithuto tse lekang ho sebelisa nanoparticles tse entsoeng ka zinc oxide, koporo oxide, joalo-joalo ho phekola ho bola ha leino.Empa bothata ke hore ho na le meno a fetang 20 molomong oa motho, 'me kaofela ha ona a kotsing ea ho holisoa ke baktheria.Ho sebelisoa khafetsa ha meriana ena ho ka bolaea lisele tse molemo esita le ho baka bothata ba ho hanyetsa lithethefatsi tsa libaktheria tse kotsi.

Ka hona, bafuputsi ba na le tšepo ea ho fumana tsela ea ho sireletsa baktheria e molemo lemenong le ho thibela ho bola ha leino.Ba ile ba lebisa tlhokomelo ea bona ho cerium oxide nanoparticles (formula ea molek'hule: CeO2).Karolo ke e 'ngoe ea lisebelisoa tsa bohlokoa tsa antibacterial' me e na le melemo ea chefo e tlaase ho lisele tse tloaelehileng le mochine oa antibacterial o thehiloeng ho fetola valence e fetohang.Ka 2019, bafuputsi ba tsoang Univesithing ea Nankai ba ile ba hlahloba ka mokhoa o hlophisitsoeng mokhoa oa ho thibela likokoana-hloko oacerium oxide nanoparticlesho Science China Materials.

Ho ea ka tlaleho ea bafuputsi sebokeng, ba ile ba hlahisa cerium oxide nanoparticles ka ho qhaqha cerium nitrate kapa ammonium sulfate metsing, 'me ba ithuta phello ea likaroloana ho "biofilm" e entsoeng ke Streptococcus mutans.Liphello li bontšitse hore le hoja cerium oxide nanoparticles e sitoa ho tlosa "biofilm" e teng, e ile ea fokotsa kholo ea eona ka 40%.Tlas'a maemo a ts'oanang, moemeli ea tsebahalang oa anti-cavity silver nitrate o ne a sitoa ho liehisa "biofilm".Tsoelopele ea "membrane".

Mofuputsi ea ka sehloohong oa morero ona, Russell Pesavento oa Univesithi ea Illinois e Chicago, o itse: “Molemo oa mokhoa ona oa phekolo ke hore o bonahala o se kotsi hakaalo libaktheria tsa molomo.Li-nanoparticles li tla thibela likokoana-hloko ho khomarela ntho le ho etsa biofilm.'Me chefo ea chefo le litlamorao tsa metabolism liseleng tsa motho tsa molomo sejaneng sa petri li tlase ho silvera nitrate kalafong e tloaelehileng. ” 

Hona joale, sehlopha se leka ho sebelisa liphahlo ho tsitsisa nanoparticles ka pH e sa nke lehlakore kapa e fokolang ea alkaline haufi le ea mathe.Nakong e tlang, bafuputsi ba tla hlahloba phello ea phekolo ena liseleng tsa motho tse karolong e ka tlaase ea tšilo ea lijo ka har'a limela tsa likokoana-hloko tsa molomo tse feletseng, e le ho fa bakuli boikutlo bo botle ba tšireletso.