Igolide lingenye yezinto ezizinze kakhulu kumakhemikhali, futhi izinhlayiya zegolide ze-nanoscale zinezakhiwo ezikhethekile zomzimba namakhemikhali.Kusukela ngo-1857, uFaraday wehlisa isixazululo samanzi se-AuCl4 nge-phosphorus ukuze athole isisombululo esibomvu se-colloidal se-nanoppowder segolide, esaphula ukuqonda kwabantu ngombala wegolide.Izinhlayiya zegolide ze-Nano nazo zitholakale zinezindawo zokuqaphela i-fluorescence, i-supramolecular kanye ne-molecular.Kungenxa yezindawo ezikhethekile zezimpushana zegolide ze-nano ukuthi babe namathemba okusebenza abanzi ngokwedlulele emikhakheni ye-biosensors, i-photochemical and electrochemical catalysis, kanye namadivayisi we-optoelectronic.Eminyakeni yamuva, ngokususelwa kuhlobo lokushintshwa okubomvu kwe-surface plasmon resonance peak ye-Au nanoparticles ngemva kokukhangiswa, ama-molecule e-DNA nama-carbohydrate alayishwe izinhlayiya ze-nano Au ahlolisisiwe futhi atholakala ewusizo emkhakheni wokuzivikela komzimba, ukulinganisa. kanye nomkhondo.

Ama-nanoparticles egolidenjengohlobo lwama-nanoparticles, akhangwa kabanzi ngenxa yokuzinza kwawo, i-homogeneity kanye ne-biocompatibility.Izakhiwo ze-plasmon resonance kanye nokuhlanganisa izinhlayiya ze-nano zegolide, kanye nokuncika kwazo endaweni ezungezile yangaphandle, kuzenza zisetshenziswe kabanzi ekuhlonzweni kombala.Amandla abikiwe okuhlanganiswa kwezinhlayiya ze-Au nano ahlanganisa i-hydrogen bonding, ukusebenzisana kwesayithi le-ionic ligand, ukuhlanganiswa kwensimbi, kanye nokufakwa komsingathi nesivakashi.Kusetshenziswa i-sodium citrate njenge-stabilizer, ama-nanoparticles egolide e-sodium citrate ahlanganiswe ngempumelelo futhi asetshenziswa njengama-colorimetric probes.Ingaphezulu le-nano probe yegolide lishajelwe kabi futhi lingahlanganiswa kalula nama-molecule athagethwe kahle ngokusebenzisa ukusebenzisana kwe-electrostatic.Kusixazululo sebhafa se-BR ku-pH 4.6, i-propranolol ishajwa kahle ngenxa ye-protonation, ngakho-ke ingahlanganiswa nama-nanoparticles egolide, okuholela ekushintsheni kombala wesistimu, ukuze kusungulwe indlela elula yokuhlonza i-colorimetric ye-propranolol .Ngesikhathi esifanayo, ngokuhlanganiswa kwezimpushana ze-nano zegolide, ukushuba kwe-RRS kohlelo nakho kuzokhula, ngakho indlela ye-RRS ene-fluorescence spectrophotometer elula njengoba umtshina usungulelwa futhi ukuze uthole i-propranolol ebucayi.Ngokusekelwe ku-sodium citrate-modified gold nan oparticles, i-colorimetric kanye nezindlela ze-RRS zokunquma i-propranolol zasungulwa.

I-Hongwu Nano inokunikezwa kwesikhathi eside futhi okuzinzile kwezinhlayiya ze-nano zegolide (Au) zekhwalithi ephezulu, ukuqinisekiswa kwekhwalithi, ukuthengiswa okuqondile kwefekthri, nezintengo ezincintisanayo.Sicela ungangabazi ukusithinta ukuze uthole ulwazi olwengeziwe.